Potensi Antimikroba Ekstrak Tumbuhan Sirih Cina (Peperomia Pellucida L. Kunth)

Abstrak

Chinese betel is a plant that has potential as a traditional medicine for treating various infectious diseases that occur in humans. Various microbes that cause infections in humans can cause dangerous diseases. In this research, bacteria that cause dysentery and fungi that cause skin infections are used as test microbes. The Chinese betel leaves tested were extracted to extract the active components contained in Chinese betel leaves using the maceration method using ethanol solvent. The bacterial test microbes were Shigella dysentriae ATCC 12037, Shigella flexneri ATCC 12022, and Shigella sonnei ATCC 25931 and the test fungi were Trichopyton menthagrophytes ATTC 52016, Microsporum canis ATCC 32699, and Pityrosporum ovale ATTC 12678. Antimicrobial testing was carried out using the agar diffusion method, using a paper disc as a backup. Chinese betel extract concentrations of 15%, 20%, 25% on Trichopyton menthagrophytes ATTC 52016 mushrooms showed an average inhibitory diameter of 10.80 mm, 12.71 mm, and 14.23 mm. Microsporum canis ATCC 32699 with an average inhibitory diameter of 10.25 mm, 12.29 mm, and 13.18 mm. Pityrosporum ovale ATTC 12678 with an average inhibitory diameter of 9.6 mm, 11.5 mm and 13.23 mm. At test substance concentrations of 10%, 20%, 30% against Shigella dysentriae ATCC 12037 bacteria it was 10.5 mm, 12.4 mm 16.4 mm, Shigella flexneri ATCC 12022 bacteria was 9.06 mm, 10.4 mm and 12 .5 mm, and Shigella sonnei ATCC 25931 bacteria was 10.3 mm, 12.4 mm and 14.5 mm.